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FARAFARA Cure FA

Iron regulatory protein 1 sustains mitochondrial iron loading and function in frataxin deficiency

Mitochondrial iron accumulation is a hallmark of diseases associated with impaired iron-sulfur cluster (Fe-S) biogenesis, such as Friedreich ataxia linked to frataxin (FXN) deficiency. The pathophysiological relevance of the mitochondrial iron loading and the underlying mechanisms are unknown.

Read More: Iron regulatory protein 1 sustains mitochondrial iron loading and function in frataxin deficiency


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Jen Farmer

Jen Farmer

Executive Director

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