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Integration of functional bacterial artificial chromosomes into human cord blood-derived multipotent stem cells.

Stem cells from a patient with a genetic disease could be used for cell therapy if it were possible to insert a functional copy of the defective gene. In this study, we investigate the transfection and subsequent integration of large genomic fragments into human cord blood-derived multipotent stem cells.

Read More: Integration of functional bacterial artificial chromosomes into human cord blood-derived multipotent stem cells.

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