Request For Proposals: Pharmacodynamic Biomarker Development
This RFP supports the discovery and validation of non-invasive and quantitative methodologies to measure the following in FRDA affected tissues (brain, spinal cord or heart):
- Frataxin protein levels
- Biochemical activities dependent on/downstream of frataxin function that can be surrogates of frataxin in inaccessible tissues
FARA will consider proof of concept and high-risk proposals, without preliminary data, provided they show a strong rationale for the proposed use and development of such biomarkers.
Informal inquiries regarding study relevance and interest to FARA are welcome and should be directed to firstname.lastname@example.org.
Please click below to submit a Letter of Intent.The LOI submission deadline is December 1, 2021.