Friedrich'a Ataxia patients have neurological impairment that causes physical impairments, but existing timed neuropsychological tests do not take this into account during scoring procedures. This paper proposes a normalization method based on the PATA Rate Task (PRT) and on the nine-hole pegboard test (9HPT) as a measure of dysarthria and upper limb dysfunction.They tested 65 healthy controls on timed neuropsychological tests (Attentional Matrices [AM], Trail Making Test, Symbol Digit Modalities Test, Verbal Fluencies) to determine the time spent on phonation or on hand movement during test execution. They developed correction formulas to normalize test times considering the patient's PRT/9HPT, their normality limits, and the test timing. They tested the method on 24 patients with Friedreich Ataxia (FRDA), as a model of motor and speech impairment.
They found that in healthy controls, phonation or hand movement is 13.5-61.7% of total test time. In FRDA patients, the effect of normalization improved all test results (range: 0.51-48.4%; p
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